Publications and Awards

2026

Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.

Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality

Nature Communications, vol. 17, (no. 1)

DOI 10.1038/s41467-025-66694-9 Article Journal

2026

Broglia L., Canale C., Vandelli A., Tartaglia G.G., Delli Ponti R.

Decoding the Structural Complexity of Viral RNAs with SHAPE to Guide Antiviral Therapeutics

Viruses, vol. 18, (no. 5)

DOI 10.3390/v18050543 Review Journal

2026

Ferolito B.R., Dashti H., Giambartolomei C., Peloso G.M., Golden D.J., Gravel-Pucillo K., Rasooly D., Horimoto A.R.V.R., Matty R., Gaziano L., Liu Y., Smit I.A., Zdrazil B., Tsepilov Y., Costa L., Kosik N., Huffman J.E., Tartaglia G.G., Bini G., Proietti G., Ioannidis H., Karim M.A., Hunter F., Hemani G., Butterworth A.S., Di Angelantonio E., Langenberg C., Ghoussaini M., Leach A.R., Liao K.P., Damrauer S., Selva L.E., Whitbourne S., Tsao P.S., Moser J., Gaunt T., Cai T., Whittaker J.C., Casas J.P., Muralidhar S., Gaziano J.M., Cho K., Pereira A.C.

Leveraging large-scale biobanks for therapeutic target discovery

Human Genetics and Genomics Advances, vol. 7, (no. 1)

DOI 10.1016/j.xhgg.2025.100556 Article Journal

2026

Fiorentino J., Monti M., Broglia L., Tartaglia G.G.

Physicochemical principles of RNA-mediated crowding

Current Opinion in Structural Biology, vol. 100

DOI 10.1016/j.sbi.2026.103334 Review Journal

2026

Broglia L., Dasti A., Antonelli M., Aoun G., DAgostino S., Vandelli A., Armaos A., Delli Ponti R., Wolf S., Klostermann M., Segura M., Tian T., Mariani D., Colantoni A., Paronetto M., Gustincich S., Zarnack K., Bechara E., Tartaglia G.G.

SAM68 is a multifunctional post-transcriptional regulator of cardiomyocyte differentiation

Nucleic Acids Research, vol. 54, (no. 10), pp. 547

DOI 10.1093/nar/gkag547. Article Journal

2026

Broglia L., Dasti A., Antonelli M.C., Aoun G., D'Agostino S., Vandelli A., Armaos A., DelliPonti R., Wolf S., Klostermann M., ArnalSegura M., Tian T.V., Mariani D., Colantoni A., Paronetto M.P., Gustincich S., Zarnack K., Bechara E., Tartaglia G.G.

SAM68 is a multifunctional post-transcriptional regulator of cardiomyocyte differentiation

Nucleic Acids Research, vol. 54, (no. 10)

DOI 10.1093/nar/gkag547 Article Journal

2026

Fiorentino J., Armaos A., Montrone C., Colantoni A., Tartaglia G.G.

scRAPID-web: a web server for predicting protein–RNA interactions from single-cell transcriptomics

BMC Genomics, vol. 27, (no. 1)

DOI 10.1186/s12864-026-12870-0 Article Journal

2026

Setti A., Bini G., Flaminia P., Maiorca V., Proietti G., Vrachnos D.M., D'Angelo A., Armaos A., Martone J., Monti M., Ruocco G., Rodolà E., Bozzoni I., Colantoni A., Tartaglia G.G.

The role of low-complexity repeats in RNA-RNA interactions and a deep learning framework for duplex prediction

Nature Communications

DOI 10.1038/s41467-026-68356-w Article Journal

2025

Vedeler A., Tartaglia G.G., Pastore A.

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

BioEssays

DOI 10.1002/bies.70019 Review Journal

2025

Foord C., Prjibelski A.D., Hu W., Michielsen L., Vandelli A., Narykov O., Evans B., Hsu J., Belchikov N., Jarroux J., He Y., Ross M.E., Hajirasouliha I., Tartaglia G.G., Korkin D., Tomescu A.I., Tilgner H.U.

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types

Nature Communications, vol. 16, (no. 1)

DOI 10.1038/s41467-025-63301-9 Article Journal

HELDA - Digital Repository of the University of Helsinki

2025

Monti M., Fiorentino J., Miltiadis-Vrachnos D., Bini G., Cotrufo T., SanchezdeGroot N., Armaos A., Tartaglia G.

catGRANULE 2.0: accurate predictions of liquid-liquid phase separating proteins at single amino acid resolution

Genome Biology, vol. 26, (no. 1)

DOI 10.1186/s13059-025-03497-7 Article Journal

2025

Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.

Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality

Nature Communications, vol. 17, (no. 1)

DOI 10.1038/s41467-025-66694-9 Article Journal

2025

Milordini G., Zacco E., Armaos A., Di Palma F., Masi M., Gilodi M., Rupert J., Broglia L., Varignani G., Oneto M., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.

Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment

bioRxiv

DOI 10.1101/2025.01.20.633558 Article E-print Archive

2025

Bini G., Tartaglia G.G.

Deep Learning Approaches to Predict RNA-RNA interactions

PhD Thesis Book

2025

Alriquet M., Arsie R., Calloni G., Tartaglia G.G., Vabulas R.M.

Deficiency of N1-Adenine Methyltransferase Aggravates RNA and Protein Aggregation

Cells, vol. 14, (no. 17)

DOI 10.3390/cells14171370 Article Journal

PubMed Central

Institutional Repository for Molecular Medicine (MDC)

2025

Luige J., Conrad T., Armaos A., Louloupi A., Vincent A., Meierhofer D., Gajhede M., Tartaglia G.G., Orom U.A.V.

Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases

Computational and Structural Biotechnology Journal, vol. 27, pp. 2719-2729

DOI 10.1016/j.csbj.2025.06.027 Article Journal

PURE Aarhus University

DOAJ

2025

Intze A., Temperini M.E., Rupert J., Polito R., Veber A., Puskar L., Schade U., Ortolani M., Zacco E., Tartaglia G.G., Giliberti V.

Effect of RNA on the supramolecular architecture of α-synuclein fibrils

Biophysical Journal

DOI 10.1016/j.bpj.2025.04.031 Article Journal

DZNE Pub

IRIS Cnr