Publications and Awards
Rehab Technologies Lab is an award-winning research line of IIT and our teams actively support the scientific community with many publications, dissemination talks and other accomplishments.
Publications
2023
Ugolini A., Vecchio D., Scarpelli R., Grimaldi B.
A new class of autophagy inhibitors for the treatment of cancer (P36)- September 10-13, 2023, Cambridge (United Kingdom)
XXII Medicinal Chemistry Symposium - SCI / RSC
Poster
Conference
2023
Palomba M., Vecchio D., Allavena G., Capaccio V., De Mei C., Scarpelli R., Grimaldi B.
Identification of a Dual Autophagy and REV-ERB Inhibitor with in Vivo Anticancer Efficacy
Journal of Medicinal Chemistry
2023
Scarpelli R., Palomba M., Vecchio D., Ottonello G., Mandrup Bertozzi S., Summa M., Armirotti A., Bertorelli R., De Mei C., Grimaldi B.
Identification of a dual REV-ERBβ and autophagy inhibitor with in vivo anticancer efficacy (P222)- September 3-7, 2023, Zagreb (Croatia)
IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
Poster
Conference
2023
Palomba M., Vecchio D., Allavena G., Capaccio V., De Mei C., Scarpelli R., Grimaldi B.
Lead optimization of a class of dual REV_ERB and autophagy inhibitors with in vivo anticancer efficacy (P45)- September 10-13, 2023, Cambridge (United Kingdom)
XXII Medicinal Chemistry Symposium - SCI / RSC
Poster
Conference
2023
Scarpelli R., Palomba M., Vecchio D., Allavena G., Capaccio V., De Mei C., Grimaldi B.
Lead optimization of the diarylalkyl amine series as dual REV_ERB and autophagy inhibitors with in vivo anticancer efficacy (P83)- September 17-20, 2023, Chieti (Italy)
XXVIII National Meeting on Medicinal Chemistry
Poster
Conference
2022
Ugolini A., Mongiardini V., Vecchio D., Scarpelli R., Grimaldi B.
Bactericidal-Autophagy Inhibitors to Treat Recurring Uropathogenic Infections and Cancer (P209). XXVII EFMC-ISMC 2022, September 4-8, 2022 - Nice (France)
EFMC International Symposium on Medicinal Chemistry
Poster
Conference
2022
Greco R., Demartini C., Zanaboni A.M., Francavilla M., Reggiani A., Realini N., Scarpelli R., Piomelli D., Tassorelli C.
Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine
Journal of Headache and Pain, vol. 23, (no. 1)
2020
Caputo S., Di Martino S., Cilibrasi V., Tardia P., Mazzonna M., Russo D., Penna I., Summa M., Bertozzi S.M., Realini N., Margaroli N., Migliore M., Ottonello G., Liu M., Lansbury P., Armirotti A., Bertorelli R., Ray S.S., Skerlj R., Scarpelli R.
Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors
Journal of Medicinal Chemistry, vol. 63, (no. 24), pp. 15821-15851
2020
Di Martino S., Tardia P., Cilibrasi V., Caputo S., Mazzonna M., Russo D., Penna I., Realini N., Margaroli N., Migliore M., Pizzirani D., Ottonello G., Bertozzi S.M., Armirotti A., Nguyen D., Sun Y., Bongarzone E.R., Lansbury P., Liu M., Skerlj R., Scarpelli R.
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors
Journal of Medicinal Chemistry, vol. 63, (no. 7), pp. 3634-3664
2016
Scarpelli R., Sasso O., Piomelli D.
A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation
ChemMedChem, pp. 1242-1251
2016
Veronesi M., Giacomina F., Romeo E., Castellani B., Ottonello G., Lambruschini C., Garau G., Scarpelli R., Bandiera T., Piomelli D., Dalvit C.
Fluorine nuclear magnetic resonance-based assay in living mammalian cells
Analytical Biochemistry, vol. 495, pp. 52-59
2016
Falchi F., Bertozzi S.M., Ottonello G., Ruda G.F., Colombano G., Fiorelli C., Martucci C., Bertorelli R., Scarpelli R., Cavalli A., Bandiera T., Armirotti A.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification
Analytical Chemistry, vol. 88, (no. 19), pp. 9510-9517
2016
Migliore M., Habrant D., Sasso O., Albani C., Bertozzi S.M., Armirotti A., Piomelli D., Scarpelli R.
Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies
European Journal of Medicinal Chemistry, vol. 109, pp. 216-237
2016
Migliore M., Pontis S., Fuentes de Arriba A.L., Realini N., Torrente E., Armirotti A., Romeo E., Di Martino S., Russo D., Pizzirani D., Summa M., Lanfranco M., Ottonello G., Busquet P., Jung K.-M., Garcia-Guzman M., Heim R., Scarpelli R., Piomelli D.
Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis
Angewandte Chemie - International Edition, vol. 55, (no. 37), pp. 11193-11197
2015
Prati F., De Simone A., Armirotti A., Summa M., Pizzirani D., Scarpelli R., Bertozzi S.M., Perez D.I., Andrisano V., Perez-Castillo A., Monti B., Massenzio F., Polito L., Racchi M., Sabatino P., Bottegoni G., Martinez A., Cavalli A., Bolognesi M.L.
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease
ACS Chemical Neuroscience, vol. 6, (no. 10), pp. 1665-1682
Awards
2024
Macaluso A., Bottino A., Pratticò F.G., Lamberti F., Galletti C., Storchi C., Podda J., Tacchino A., Brichetto G., Boccardo N., et al.
Best Session Presentation - Executive Control in a Mixed Reality Exergame for Motor-Cognitive Rehabilitation in Multiple Sclerosis
2022
Maludrottu S., Laffranchi M., Vassallo C., Vaccaro R., De Michieli L.
iF DESIGN AWARD 2022 - Twin Exoskeleton
2021
Laffranchi M., Traverso S., Vaccaro R., Maludrottu S., Poli F., De Bartolomeis L., Diamanti G., Gruppioni E., De Michieli L.
Good Design
2020
Laffranchi M.
Robotics 2020 Young Investigator Award
2020
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
XXVI Compasso d'oro
2019
Colombi I.
PhD thesis award in Neuroengineering "MASSIMO GRATTAROLA" (17^ Ed.)
2018
Laffranchi M., Boccardo N., Traverso S., Lince A., Canepa M., Saglia J., Gruppioni E., Sacchetti R., Diamanti G., Poli F., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
Good Design
2018
Semprini M.
selected as "reviewer of the year" for Journal of Neural Engineering