Publications and Awards
Rehab Technologies Lab is an award-winning research line of IIT and our teams actively support the scientific community with many publications, dissemination talks and other accomplishments.
Publications
2023
Demuro S., Di Martino R.M.C., Sauvey C., Tripathi S.K., Ortega J. A., Russo D., Penna I., Myers S. H., Bandiera T., Girotto S., Abagyan R., Cavalli A.
Design and synthesis of triple protein kinase inhibitors: paving the way towards novel CNS tools to reverse the aberrant tau phosphorylation
ACS Spring 2023 meeting
Poster
Conference
2022
Orioli R., Marotta G., Russo D., Penna I., Rosini M., Ortega J.A., Minarini A.
DESIGN AND SYNTHESIS OF AMMINOTIAZOLE DERIVATIVES AS DUAL LIGANDS TO GSK-3B AND FYN IN THE STUDY OF NEURODEGENERATIVE DISEASES
XXI Giornata della Chimica dell'Emilia Romagna (Bologna)
Poster
Conference
2022
Demuro S., Di Martino R.M.C., Ortega J.A., Sauvey C., Shi D., Tripathi S., Balboni B., Girotto S., Russo D., Penna I., Bandiera T., Ballatore C., Abagyan R., Cavalli A.
Development of multitarget-directed ligands (MTDLs) protein kinases inhibitors to tackle central nervous system (CNS)-related disorders
ACS Spring 2022 meeting
Abstract Report
Conference
2022
Mazzarella M.A., Berti F., Russo D., Penna I., Bottegoni G., Reggiani A., Bertozzi F., Bandiera T.
Identification of dual inhibitors to hit inflammation and neurodegeneration for multiple sclerosis therapy
European School of Medicinal Chemistry, 41st Advanced Course of Medicinal Chemistry and Seminar for PhD students
Poster
Conference
2022
Balboni B., Tripathi S.K., Veronesi M., Russo D., Penna I., Giabbai B., Bandiera T., Storici P., Girotto S., Cavalli A.
Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays
International Journal of Molecular Sciences, vol. 23, (no. 7)
2021
Marotta G., Di Martino R.M.C., Russo D., Penna I., Rosini M., Ortega J.A., Minarini A.
DESIGN AND SYNTHESIS OF MULTITARGET-DIRECTED LIGANDS TO TACKLE NEUROINFLAMMATION
XX Giornata della Chimica dell’Emilia-Romagna (GdC-ER)
Poster
Conference
2021
Marotta G., Di Martino R.M.C., Russo D., Penna I., Rosini M., Ortega J.A., Minarini A.
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease
13th Young Medicinal Chemist's Symposium
Poster
Conference
2021
Demuro S., Di Martino R.M.C., Ortega J.A., Sauvey C., Shi D., Tripathi S., Balboni B., Girotto S., Russo D., Penna I., bandiera T., Ballatore C., Abagyan R., Cavalli A.
DEVELOPMENT OF MULTITARGET-DIRECTED LIGANDS (MTDLS) PROTEIN KINASES INHIBITORS TO TACKLE CENTRAL NERVOUS SYSTEM (CNS)-RELATED DISORDERS
EFMC-ISMC & EFMC-YMCS 2021
Poster
Conference
2021
Di Fruscia P., Carbone A., Bottegoni G., Berti F., Giacomina F., Ponzano S., Pagliuca C., Fiasella A., Pizzirani D., Ortega J.A., Nuzzi A., Tarozzo G., Mengatto L., Giampa R., Penna I., Russo D., Romeo E., Summa M., Bertorelli R., Armirotti A., Bertozzi S.M., Reggiani A., Bandiera T., Bertozzi F.
Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-CovalentN-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration
Journal of Medicinal Chemistry, vol. 64, (no. 18), pp. 13327-13355
2021
Balboni B., Tripathi S., Veronesi M., Russo D., Penna I., Giabbai B., Storici P., Bandiera T., Girotto S., Cavalli A.
Drug-Discovery Pipeline for Structural and Biophysical Characterization of GSK-3β Inhibitors
BSI structural biology conference
Poster
Conference
2020
Caputo S., Di Martino S., Cilibrasi V., Tardia P., Mazzonna M., Russo D., Penna I., Summa M., Mandrup Bertozzi S., Realini N., Margaroli N., Migliore M., Ottonello G., Liu M., Lansbury P., Armirotti A., Bertorelli R., Ray S.S., Skerlj R., Scarpelli R.
Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors
Journal of Medicinal Chemistry, vol. 63, (no. 24), pp. 15821-15851
2020
Brindani N., Gianotti A., Giovani S., Giacomina F., Di Fruscia P., Sorana F., Bertozzi S.M., Ottonello G., Goldoni L., Penna I., Russo D., Summa M., Bertorelli R., Ferrera L., Pesce E., Sondo E., Galietta L.J.V., Bandiera T., Pedemonte N., Bertozzi F.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators
Journal of Medicinal Chemistry, vol. 63, (no. 19), pp. 11169-11194
2020
Di Martino S., Tardia S., Cilibrasi V., Caputo S., Mazzonna M., Russo D., Penna I., Realini N., Margaroli N., Migliore M., Pizzirani D., Ottonello G., Mandrup Bertozzi S., Armirotti A., Nguyen D., Sun Y., Bongarzone E., Lansbury P., Liu M., Skerlj R. T., Scarpelli R.
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors.
Journal of Medicinal Chemistry
2020
Di Martino R.M.C., Bottegoni G., Seghetti F., Russo D., Penna I., De Simone A., Ottonello G., Mandrup Bertozzi S., Armirotti A., Bandiera T., Belluti F., Cavalli A.
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
ChemMedChem, vol. 15, (no. 11), pp. 949-954
2020
Seghetti F., Di Martino R.M.C., Bottegoni G., Russo D., Penna I., Bandiera T., Cavalli A., Belluti F.
NOVEL DUAL D3R/GSK-3β MODULATORS: AN INNOVATIVE MULTITARGET STRATEGY FOR BIPOLAR DISORDER
EFMC-ISMC & EFMC-YMCS
Poster
Conference
Awards
2022
Maludrottu S., Laffranchi M., Vassallo C., Vaccaro R., De Michieli L.
iF DESIGN AWARD 2022 - Twin Exoskeleton
2021
Laffranchi M., Traverso S., Vaccaro R., Maludrottu S., Poli F., De Bartolomeis L., Diamanti G., Gruppioni E., De Michieli L.
Good Design
2020
Laffranchi M.
Robotics 2020 Young Investigator Award
2020
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
XXVI Compasso d'oro
2019
Colombi I.
PhD thesis award in Neuroengineering "MASSIMO GRATTAROLA" (17^ Ed.)
2018
Laffranchi M., Boccardo N., Traverso S., Lince A., Canepa M., Saglia J., Gruppioni E., Sacchetti R., Diamanti G., Poli F., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
Good Design
2018
Semprini M.
selected as "reviewer of the year" for Journal of Neural Engineering
2012
Laffranchi M.
Best Jubilee Video Award