Publications and Awards
Rehab Technologies Lab is an award-winning research line of IIT and our teams actively support the scientific community with many publications, dissemination talks and other accomplishments.
Publications
2023
Melloni A., Serani A., Tucci V.
Parental genome and brain functions: The case of genomic imprinting
Principles of Gender-Specific Medicine: Sex and Gender-Specific Biology in the Postgenomic Era, pp. 301-312, Publisher: Elsevier
2023
Sanguigno L., Guida N., Anzilotti S., Cuomo O., Mascolo L., Serani A., Brancaccio P., Pennacchio G., Licastro E., Pignataro G., Molinaro P., Annunziato L., Formisano L.
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death
International Journal of Biological Sciences, vol. 19, (no. 9), pp. 2695-2710
2022
Calabrese L., Serani A., Natale S., Tedeschi V., Guida N., Valsecchi V., Secondo A., Formisano L., Annunziato L., Molinaro P.
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene
Cell Calcium, vol. 102
2021
Guida N., Mascolo L., Serani A., Cuomo O., Anzilotti S., Brancaccio P., Pignataro G., Molinaro P., Annunziato L., Formisano L.
GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A) Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of Histone-3) Upregulates NCX3 (Na+-Ca2+Exchanger 3) Transcription and Contributes to Ischemic Preconditioning Neuroprotection
Stroke, vol. 52, (no. 11), pp. 3680-3691
2021
Guida N., Sanguigno L., Mascolo L., Calabrese L., Serani A., Molinaro P., Lau C.G., Annunziato L., Formisano L.
The Transcriptional Complex Sp1/KMT2A by Up-Regulating Restrictive Element 1 Silencing Transcription Factor Accelerates Methylmercury-Induced Cell Death in Motor Neuron-Like NSC34 Cells Overexpressing SOD1-G93A
Frontiers in Neuroscience, vol. 15
2020
Molinaro P., Natale S., Serani A., Calabrese L., Secondo A., Tedeschi V., Valsecchi V., Pannaccione A., Scorziello A., Annunziato L.
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms
Cell Calcium, vol. 87
2020
Natale S., Anzilotti S., Petrozziello T., Ciccone R., Serani A., Calabrese L., Severino B., Frecentese F., Secondo A., Pannaccione A., Fiorino F., Cuomo O., Vinciguerra A., D'Esposito L., Sadile A.G., Cabib S., Di Renzo G., Annunziato L., Molinaro P.
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory
Molecular Neurobiology, vol. 57, (no. 5), pp. 2358-2376
2020
Formisano L., Laudati G., Guida N., Mascolo L., Serani A., Cuomo O., Cantile M., Boscia F., Molinaro P., Anzilotti S., Pizzorusso V., Di Renzo G., Pignataro G., Annunziato L.
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage
Journal of Cerebral Blood Flow and Metabolism, vol. 40, (no. 10), pp. 2081-2097
2020
Valsecchi V., Anzilotti S., Serani A., Laudati G., Brancaccio P., Guida N., Cuomo O., Pignataro G., Annunziato L.
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA
Molecular Therapy, vol. 28, (no. 4), pp. 1154-1166
2020
Formisano L., Guida N., Mascolo L., Serani A., Laudati G., Pizzorusso V., Annunziato L.
Transcriptional and epigenetic regulation of ncx1 and ncx3 in the brain
Cell Calcium, vol. 87
2019
Cuomo O., Cepparulo P., Anzilotti S., Serani A., Sirabella R., Brancaccio P., Guida N., Valsecchi V., Vinciguerra A., Molinaro P., Formisano L., Annunziato L., Pignataro G.
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats
Molecular Therapy - Nucleic Acids, vol. 18, pp. 1063-1071
2019
Laudati G., Mascolo L., Guida N., Sirabella R., Pizzorusso V., Bruzzaniti S., Serani A., Di Renzo G., Canzoniero L.M.T., Formisano L.
Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway
NeuroToxicology, vol. 71, pp. 6-15
2018
Guida N., Valsecchi V., Laudati G., Serani A., Mascolo L., Molinaro P., Montuori P., Renzo G.D., Canzoniero L.M., Formisano L.
The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons
Toxicological Sciences, vol. 163, (no. 2), pp. 569-578
2017
Guida N., Laudati G., Serani A., Mascolo L., Molinaro P., Montuori P., Di Renzo G., Canzoniero L.M.T., Formisano L.
The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death
Biochemical Pharmacology, vol. 142, pp. 229-241
2013
Costa P.M., Cardoso A.L., Mendonca L.S., Serani A., Custodia C., Conceicao M., Simoes S., Moreira J.N., De Almeida L.P., De Lima M.C.P.
Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: A promising system for glioblastoma treatment
Molecular Therapy - Nucleic Acids, vol. 2
Awards
2024
Macaluso A., Bottino A., Pratticò F.G., Lamberti F., Galletti C., Storchi C., Podda J., Tacchino A., Brichetto G., Boccardo N., et al.
Best Session Presentation - Executive Control in a Mixed Reality Exergame for Motor-Cognitive Rehabilitation in Multiple Sclerosis
2022
Maludrottu S., Laffranchi M., Vassallo C., Vaccaro R., De Michieli L.
iF DESIGN AWARD 2022 - Twin Exoskeleton
2021
Laffranchi M., Traverso S., Vaccaro R., Maludrottu S., Poli F., De Bartolomeis L., Diamanti G., Gruppioni E., De Michieli L.
Good Design
2020
Laffranchi M.
Robotics 2020 Young Investigator Award
2020
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
XXVI Compasso d'oro
2019
Colombi I.
PhD thesis award in Neuroengineering "MASSIMO GRATTAROLA" (17^ Ed.)
2018
Laffranchi M., Boccardo N., Traverso S., Lince A., Canepa M., Saglia J., Gruppioni E., Sacchetti R., Diamanti G., Poli F., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
ADI Design Index
2018
Laffranchi M., Boccardo N., Traverso S., Lombardi L., Canepa M., Lince A., Semprini M., Saglia J.A., Naceri A., Sacchetti R., et al.
Good Design
2018
Semprini M.
selected as "reviewer of the year" for Journal of Neural Engineering